The Protein Interaction (PIN) module catalogues every known interaction between gene products associated with ASD, including both protein-protein and protein-nucleic acid interactions.
Studying the many interactions that take place between proteins is crucial to understanding their functions. The PIN module of SFARI Gene serves as an up-to-date reference for all known direct interactions occurring between gene products implicated in ASD.
Published data related to an individual protein are manually reviewed and verified by our researchers. Once the evidence has been analyzed, the proteins are added into the module and organized into the genetic categories below. The PIN Module is designed to help accelerate ASD research by acting as a bioinformatics platform for network biology analysis of the molecular pathways underlying ASD pathogenesis.